Why Humans Can’t Make Vitamin C: The Missing Gene (GULO)
Did you know most animals can produce their own vitamin C? Humans, guinea pigs, and certain bats are rare exceptions — and the reason why might surprise you. It all comes down to a little gene called L-gulonolactone oxidase (GULO). This gene is essential for converting glucose into vitamin C—a crucial nutrient for our health. Millions of years ago, humans, along with a select few other species, lost this gene. The prevailing theory suggests that our ancestors thrived on diets rich in vitamin C from fruits and vegetables, making the gene redundant. However, as modern diets often fall short in providing adequate amounts of this vital nutrient, the absence of GULO has become increasingly relevant. This article explains why humans can’t make vitamin C and how liposomal C offers a smart solution.
Why This Matters Today
Vitamin C is not just a trendy supplement; it plays several critical roles in our bodies:
Collagen Production: Essential for maintaining healthy skin, joints, and gums.
Immune Function: Supports your body’s defense mechanisms against illnesses.
Antioxidant Defense: Protects cells from damage caused by free radicals.
In today’s fast-paced world filled with stress and less-than-ideal eating habits, many people fail to get enough vitamin C. Even without experiencing full-blown scurvy—characterized by fatigue and bleeding gums—low levels of vitamin C can silently affect overall wellness. Since humans can’t make vitamin C, it’s essential to get adequate amounts from your diet and supplements.
Why Humans Can’t Make Vitamin C: A Deeper Dive into the GULO Gene
Let’s dive deeper into the curious case of the GULO gene. This diminutive piece of genetic code—by the name of L-gulonolactone oxidase—served as our ancestors’ key to synthesizing vitamin C from glucose. Imagine a time when fresh fruits and vibrant vegetables were abundant, and our bodies didn’t have to rely on external sources for this essential nutrient. However, over millions of years, human evolution took a twist: we lost the ability to produce vitamin C due to mutations in the GULO gene. It seems our diet was so rich in vitamin C that our bodies collectively decided, “Hey, we can skip this step!”
Today, however, it’s a different story. Our modern diets often lack sufficient vitamin C, pushing us into a nutritional corner where we can no longer rely on internal synthesis. The absence of GULO makes us dependent on dietary sources or supplements to meet our needs.
This genetic quirk isn’t just a trivial fact; it has real implications for health:
Dietary Deficiency: Many people today consume fewer fruits and vegetables than recommended, making deficiencies commonplace.
Vulnerable Populations: Certain groups—like those under stress, elderly individuals, or those with specific dietary restrictions—are at an even greater risk of inadequate vitamin C intake.
Ongoing Research: Scientists continue exploring how this missing gene affects not only individual health but also broader public health issues related to nutrition.
Why Liposomal Vitamin C Is Superior
When it comes to vitamin C, not all supplements are created equal. While traditional ascorbic acid may have been the go-to option for years, many health enthusiasts are turning to Liposomal Vitamin C for a reason. But why is it considered superior?
Standard vitamin C supplements often face a significant hurdle: absorption. The body has a limit on how much ascorbic acid it can effectively absorb at one time, especially at higher doses. This can lead to gastrointestinal distress—a fancy way of saying you might find yourself making frequent trips to the restroom.
Enter liposomal vitamin C, which utilizes cutting-edge liposomal encapsulation technology. This method creates tiny fat-based “bubbles” (liposomes) that encapsulate the vitamin C, allowing it to be absorbed more effectively into your bloodstream without the gastrointestinal side effects associated with larger doses of regular vitamin C.
Better Absorption
For those who struggle with absorption issues—perhaps due to digestive conditions or simply aging—liposomal vitamin C can be a game-changer. These liposomes protect the vitamin during its journey through your digestive tract, ensuring that more of it gets delivered where it’s needed most: inside your cells.
Higher Bioavailability
Liposomal vitamin C boasts significantly higher bioavailability compared to traditional forms. This means you can achieve therapeutic levels without needing to take massive doses that may upset your stomach. Since humans can’t make vitamin C, this enhanced delivery system is a real advantage for maintaining optimal health.
No More GI Distress: Many users report feeling more energized and experiencing fewer digestive issues when switching to liposomal forms.
Effective Immune Support: Liposomal vitamin C aids in bolstering your immune system efficiently—helping you stay resilient against colds and other illnesses.
“Liposomal Vitamin C isn’t just a trend; it’s an evolution in how we think about nutrient absorption!”
Practical Tips for Maintaining Healthy Vitamin C Levels
Incorporate Vitamin C-rich Foods: Bell peppers, citrus fruits like oranges and lemons, and antioxidant-packed berries.
Snack Smart: Swap processed snacks for fruits like strawberries or apples.
Opt for Quality Supplements: Liposomal vitamin C offers superior absorption.
Consider Timing: Consuming vitamin C with meals may enhance absorption.
Manage Stress Levels: Stress can deplete vitamin C, so practice mindfulness techniques like meditation or yoga.
“A small change in diet can lead to significant benefits in wellness—so let’s get creative with our vitamin C sources!”
Final Thoughts
While nature once equipped us to produce our own vitamin C, modern life requires us to be proactive. Since humans can’t make vitamin C, it’s essential to be mindful of both dietary sources and the quality of any supplements you use.
Take Action Now
Want to make sure you’re choosing the best liposomal supplements? Download my free Smart Guide to Liposomal Supplements to learn what to look for, which nutrients benefit most from liposomal delivery, and how to maximize absorption. Click here to get your free guide now and take the guesswork out of supplementation!
Already know what you want? Explore my carefully curated Fullscript supplement catalog to find professional-grade liposomal vitamin C and other health essentials.
Autophagy (pronounced aw-TAW-fuh-jee) is your body’s built-in self-cleaning system. The word comes from Greek and means “self-eating.” Sounds awful —but it’s one of the healthiest things your body can do. During this process, cells break down and recycle damaged or unused components to generate energy and support healing.
Think of it like your body’s own cleanup crew: damaged proteins and worn-out parts are wrapped in a bubble-like membrane called an autophagosome, delivered to the lysosome, and digested for reuse. The lysosome is a specialized part of the cell packed with powerful enzymes. Once it fuses with the autophagosome, it digests the unwanted material inside, turning it into usable energy or raw materials for cellular repair. This natural process helps maintain balance and vitality on a cellular level.
Why Cellular Clean-Up Matters
When working efficiently, autophagy helps you stay younger, healthier, and more resilient. Some of its most important health benefits include:
Slowing aging by clearing out cellular waste
Protecting the brain and nervous system
Reducing inflammation and oxidative stress
Strengthening immune defenses
Supporting better metabolism and insulin function
This biological renewal system also kicks in when your body faces mild stress—like fasting or intense exercise—helping you adapt and grow stronger.
Fasting as a Trigger for Renewal
One of the most effective and well-documented ways to activate autophagy is through intermittent fasting. After about 12–16 hours without food, insulin levels drop, and your body begins breaking down internal components for fuel.
Personally, I follow a 16:8 intermittent fasting schedule several days a week, and I’ve experienced:
Steady weight loss
Better digestion
Improved blood sugar control
Noticeably increased energy
This natural shift in metabolism allows your body to clear out what it no longer needs—revitalizing cells from the inside out.
How Low-Carb Eating Supports This Process
Adopting a carnivore-inspired or low-carb diet also contributes to cellular renewal. With fewer blood sugar spikes and lower insulin levels, your body becomes more efficient at burning fat and reusing damaged components.
Ketosis, often triggered by fasting or high-fat diets, enhances this cellular repair response—particularly in the brain and liver.
Simple Ways to Support Cellular Health
Want to encourage autophagy without overthinking it? Here are a few practical steps you can take:
Fast for 14–18 hours a few times per week
Exercise regularly—especially strength training and cardio
Prioritize quality sleep
Minimize sugar and snacking between meals
Consider nutrients like green tea extract, spermidine, or resveratrol
Looking for professional-grade support? Visit my online supplement dispensary to browse options that promote metabolic balance and cellular vitality.
Final Thoughts on Cellular Self-Cleansing
Autophagy is more than a trendy term—it’s a critical part of your body’s defense and repair system. Through smart lifestyle choices like fasting, clean eating, and movement, you can harness its power for better energy, stronger immunity, and greater longevity.
At ToothWiz Health, we believe wellness starts from within—at the cellular level. By supporting these internal processes naturally, you give your body the tools it needs to heal, renew, and thrive.
We’ve all woken up, taken a deep breath, and been greeted by a not-so-fresh surprise—morning breath. It’s the kind of wake-up call that leaves you wondering if you mistakenly brushed your teeth with a garlic clove instead of toothpaste! While it’s a universal experience, the science behind morning breath remains a mystery for many. Why does it happen, and more importantly, how can we tackle it?
Morning breath is primarily caused by a reduction in saliva production while we sleep. Saliva plays a crucial role in our oral health; it helps wash away food particles and neutralizes harmful bacteria. When nighttime hits, our saliva production decreases significantly, creating the perfect environment for bacteria to thrive. As these bacteria feast on leftover food particles in your mouth, they produce sulfur compounds that contribute to that less-than-pleasant odor.
Interestingly, factors like diet can also play a role in bad breath in the morning. Consuming sugary or acidic foods before bed may further upset the delicate balance of bacteria in your mouth. Keeping an eye on what you eat may just be the ticket to fresher mornings. Sometimes, however, morning breath may indicate deeper issues—like chronic halitosis or even sinus problems. If you’re consistently experiencing bad breath regardless of your oral hygiene routine, it might be time to chat with your dentist about potential underlying causes.
The good news? There are multiple ways to combat morning breath effectively! From staying hydrated and practicing nasal breathing to incorporating oil pulling into your routine or consuming probiotics for oral health—small changes can yield big results. It’s all about empowering ourselves with knowledge and effective dental hygiene habits.
Understanding the Causes of Bad Morning Breath
Understanding the causes of morning breath requires a closer look at the intricate dance between our mouths and bacteria during those nightly hours. As we sleep, our bodies enter a state of rest—and so does our saliva production, which plummets significantly. This reduction in saliva creates a dry environment that is less capable of washing away food particles and neutralizing harmful bacteria.
Bacteria that thrive in your mouth can ramp up their activity during the night. While some bacteria are harmless, others produce volatile sulfur compounds (VSCs) as they digest leftover food particles. These VSCs are primarily responsible for that morning breath aroma.
Dehydration: Not drinking enough water throughout the day can exacerbate saliva reduction at night. A study indicated that dehydration can lead to a 50% decrease in salivary flow, paving the way for bacterial growth.
Mouth Breathing: If you’re a nighttime mouth breather—often due to nasal congestion—you may be setting yourself up for worse breath.
Dietary Choices: What you snack on before bed matters! Foods high in sugar or acidity can alter your mouth’s pH and invite bad bacteria.
Moreover, there’s growing research into how gut health may connect with oral health. The gut microbiome can affect our overall health, including our breath. For instance, an imbalance in gut bacteria might lead to halitosis that manifests itself more prominently when you wake up.
“Regular check-ups and open communication with your dentist are key to maintaining not just fresh breath but also overall oral health.”
When Morning Breath Signals Bigger Health Issues
Chronic Halitosis
If you find yourself constantly battling bad breath in the morning, it could be a sign of chronic halitosis. This condition is often linked to factors like poor oral hygiene, gum disease, or even systemic health issues.
Gum Disease
One of the most common culprits behind persistent bad breath is gum disease. This bacterial infection affects the tissues surrounding your teeth, leading to serious consequences if left untreated.
Sinus Problems
If you wake up with morning breath and nasal congestion or post-nasal drip, sinus infections or allergies might be the cause.
Dental Hygiene Habits
Are you following through on essentials like brushing and flossing? Neglecting these can lead to plaque and chronic halitosis.
Dietary Influences
Foods rich in sugar and acid can affect oral bacteria and promote odor. Limiting these may improve your breath quality.
“Listen to your body! Persistent morning breath could be more than a nuisance; it might be an early warning sign requiring professional insight.”
Proven Ways to Stop Morning Breath Naturally
Stay Hydrated: Drink at least eight glasses of water a day to support saliva production.
Brush and Floss at Night: This removes plaque and reduces bacteria growth overnight.
Mouthwash: Use alcohol-free options with cetylpyridinium chloride or essential oils.
Tongue Scraping: Clean your tongue gently from back to front to remove odor-causing bacteria.
Avoid Late-Night Snacks: Especially those with sugar or acid content.
Essential Oils: Peppermint and tea tree oils fight bacteria. Use as rinses or in diffusers.
Baking Soda Toothpaste: Helps neutralize odors and clean teeth naturally.
Mouthwash: Choose alcohol-free options to prevent dry mouth.
Tongue Cleaners: A simple tool that can remove odor-causing residue.
“Supportive products play an essential role in oral health—pair them with good habits, and you’ve got a winning combo!”
Morning breath is a common yet manageable condition with some understanding and proactive care. By addressing its root causes and adapting effective dental hygiene habits, you can enjoy waking up feeling refreshed every day.
Want a printable checklist of ways to beat morning breath? Download it here.
Did you know that oral health deficiencies—like those caused by gum disease or missing teeth—can impact your entire body? From nutrient loss to immune disruption, poor dental health often leads to deeper wellness issues. In this article, we’ll explore what causes these deficiencies and how to fix them naturally.
Table of Contents
Why Oral Health and Nutrition Are So Closely Linked
Common Nutrients Lost Due to Oral Health Deficiencies
Who’s Most at Risk (It’s Not Just Older Adults)
Signs Your Body Is Lacking Key Nutrients
Rebuilding Health After Oral Health Deficiencies
Targeted Supplements to Address Oral Health Deficiencies
Final Thoughts: Your Mouth Might Be Talking—Are You Listening?
1. Why Oral Health and Nutrition Are So Closely Linked
Your mouth is the gateway to your body. If you’re struggling with gum disease, missing teeth, or painful chewing, your diet often takes a hit—and that can lead to a ripple effect of oral health deficiencies and nutrient loss.
According to the National Institutes of Health, people with poor oral health often consume fewer fruits, vegetables, and high-fiber foods due to chewing discomfort.
2. Common Nutrients Lost Due to Oral Health Deficiencies
Here are some of the most common nutrient gaps in people with impaired chewing or chronic dental issues:
Nutrient
Why It Matters
What Happens When You’re Deficient
Vitamin C
Critical for gum health and collagen repair
Bleeding gums, slow healing
Vitamin D
Essential for bone and tooth strength
Weak bones, gum inflammation
Calcium
Builds and maintains jawbone and teeth
Bone loss, loose teeth
Magnesium
Supports strong enamel and muscle function
Cramps, anxiety, fatigue
B Vitamins
Needed for energy and healthy oral tissue
Mouth sores, fatigue, poor healing
Zinc
Helps fight infection and supports taste
Impaired taste, slow wound healing
3. Who’s Most at Risk?
You might think this only affects older adults with full dentures—but the truth is, anyone with compromised oral function is vulnerable, including:
People with missing teeth or poor-fitting dentures
Individuals with gum disease (periodontitis)
Patients recovering from dental surgery
Older adults with decreased appetite or chewing power
Those on soft-food diets due to pain or sensitivity
4. Signs Your Body Is Lacking Key Nutrients
Some signs sneak up slowly. Look out for:
Persistent mouth sores or slow-healing cuts
Fatigue or muscle cramps
Brittle nails or thinning hair
Irritability or poor sleep
Craving junk food or sugar
Bad breath that doesn’t go away
Many of these can be tied back to gut health and nutrient absorption—two areas your dental condition affects more than you think.
5. Rebuilding Health After Oral Health Deficiencies
✅ Avoid sugary, ultra-processed options—even if they’re easy to chew
✅ Get regular dental checkups to restore function and comfort
✅ Reintroduce fiber gradually with cooked greens or soaked chia
✅ Consider high-quality supplement support to cover gaps
6. Targeted Supplements to Address Oral Health Deficiencies
Here are my top picks based on 30+ years of dental experience and nutritional knowledge. These are also available through my online wellness shop:
1. Vitamin D + K2
Supports calcium absorption and helps prevent bone loss in the jaw.
2. Magnesium Breakthrough (by BIOptimizers)
A highly absorbable blend that supports muscle relaxation, digestion, and oral function.
👉 Get 10% off here using code SAVE10
3. P3-OM Probiotic
Boosts digestion and immune support—key when your diet is restricted.
4. Omega-3 Fatty Acids
Help reduce gum inflammation and support heart and brain health.
5. Zinc + Vitamin C Combo
Essential for tissue repair, immune strength, and gum healing.
🛒 Fullscript gives you access to professional-grade supplements, not found in stores. You can browse my recommendations here.
7. Final Thoughts: Your Mouth Might Be Talking—Are You Listening?
Poor oral health doesn’t stop at your teeth. It can affect digestion, immunity, energy, and even emotional well-being. The good news? Once you spot the connection, it’s easier to fix.
Supporting your body with the right nutrients—through food and supplements—can help you bounce back and feel better from the inside out.
✅ Want a Simple Guide?
I’ve created a free downloadable checklist: “Top 10 Supplements for a Healthy Mouth & Body After 60” — coming soon!
Many people struggle with bloating, gas, and indigestion without realizing that their bodies may lack the necessary digestive enzymes to properly break down food. Poor digestion can lead to nutrient deficiencies, gut inflammation, and discomfort after meals. Digestive enzyme supplements can help by assisting your body in breaking down proteins, fats, and carbohydrates more efficiently.
In this article, we’ll explore:
How digestive enzymes work
Who needs them
The best digestive enzyme supplements
Why MassZymes is the top choice
How Do Digestive Enzymes Work?
Digestive enzymes are proteins that speed up the breakdown of food into smaller, absorbable nutrients. Your body naturally produces enzymes in the mouth, stomach, pancreas, and small intestine. However, factors like aging, stress, poor diet, and gut imbalances can reduce enzyme production, leading to poor digestion and nutrient absorption.
Who Needs Digestive Enzymes?
You might benefit from a digestive enzyme supplement if you:
Experience bloating, gas, or indigestion after meals.
Struggle with protein digestion (feeling heavy after eating meat).
Have a history of low stomach acid (hypochlorhydria).
Follow a high-protein diet (keto, paleo, carnivore).
Have food intolerances (such as lactose intolerance).
Want to boost nutrient absorption and overall gut health.
Most people think digestion starts in the stomach, but it actually begins in the mouth. Your saliva contains enzymes like amylase, which start breaking down carbohydrates before food even reaches your stomach.
However, poor digestion can impact oral health in several ways:
Acid Reflux & Tooth Erosion – Poor digestion can lead to acid reflux, which bathes teeth in stomach acid, weakening enamel.
Bad Breath & Gut Dysbiosis – A sluggish digestive system can cause an imbalance in gut bacteria, leading to chronic bad breath (halitosis).
Nutrient Deficiencies & Gum Health – If you’re not absorbing vitamins properly, your gums and teeth may suffer. Vitamin D, K2, and minerals like magnesium are essential for strong enamel and healthy gums.
💡 Fixing digestion helps protect your teeth! By improving enzyme activity and gut health, you can enhance nutrient absorption, reduce acid reflux, and support a healthier mouth.
If you experience bloating, indigestion, or nutrient absorption issues, a high-quality digestive enzyme supplement like MassZymes can make a significant difference in your gut health and overall well-being.
Dr. Richard Walicki is a dentist practicing general and cosmetic dentistry. While we hope you find the information contained herein interesting and useful, this blog is for informational purposes and is not intended to diagnose any oral disease. Dental conditions should be evaluated by your dental health professional or a qualified specialist.
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